蒙古族、朝鲜族和壮族中腺苷酸激酶、腺苷脱氨酶、血清触珠蛋白、α1-抗胰蛋白酶的多态性

人类学学报 ›› 1987, Vol. 6 ›› Issue (02): 96-102.

蒙古族、朝鲜族和壮族中腺苷酸激酶、腺苷脱氨酶、血清触珠蛋白、α1-抗胰蛋白酶的多态性

徐玖瑾,崔梅影,李实喆,陈良忠,杜若甫,H.W.Goedde,H.G.Benkmann,G.Kriese,P.Bogdanski

出版日期:1987-06-15 发布日期:1987-06-15

The polymorphism of adenylate kinase, adenosine deaminase, haptoglobin and a1-antitrypsin in Mongolian, Korean and Zhuang populations of China

Xu Jiujin, Cui Meiying, Li Shizhe, Chen Liangzhong, Du Ruofu, H. W. Goedde, H. G. Benkman, G. Kriese, P. Bogdanski

Online:1987-06-15 Published:1987-06-15

摘要/Abstract

摘要： 调查了中国内蒙古的蒙古族、吉林的朝鲜族和广西壮族的红细胞腺苷酸激酶(AK)、腺苷脱氨酶(ADA)及血清触珠蛋白(Hp)、a1-抗胰蛋白酶(a1-AT)的遗传多态性。蒙古族、朝鲜族、壮族的基因频率:AK11分别为0.9843、1.0000、1.0000;ADA1分别为0.9529、0.9468、0.9573;Hp1分别为0.2597、0.3152、0.3571;在a1-AT中PiM分别为0.9953、0.9953、0.9928,Pis分别为0.0000、0.0000、0.0072,PiF分别为0.0047、0.0047、0.0000。x2检验表明,三个民族各项指标的表型观察值都符合Hardy-Weinberg法则。

关键词: 腺苷酸激酶;腺苷脱氨酶;血清触珠蛋白;a1-抗胰蛋白酶;多态性;中国少数民族

Abstract: The genetic polymorphism of adenylate kinase (AK) , adenosine deaminase (ADA) , haptoglobin (Hp) and ar-antitrypsin (ai-TA) was investigated in the Mongolian of Inner Mongolian Autonomous Region, Korean of Jilin Province and Zhuang of Guangxi Zhuang Autonomous Region, in China. The gene frequencies of Mongolian, Korean and Zhuang were: AK.11-0. 9843, 1. 0000, 1. 0000; ADA1-0. 9529, 0. 9468, 0. 9573; Hp1-0. 2597, 0. 3152, 0. 3571; PiM-0. 9953, 0. 9953, 0. 9928; Pi°-0. 0000, 0. 0000, 0. 0072; PiF-0. 0047, 0. 0047, 0. 0000, respectively. The x2test showed that all of the observed distributions of phenotypes of four genetic markers in Mongolian, Ko- rean and Zhuang populations were consistent with the Hardy-Weinberg’s law.

Key words: AK; ADA; Hp; a1-AT; Polymosphism; National minorities in China

徐玖瑾,崔梅影,李实喆,陈良忠,杜若甫,H.W.Goedde,H.G.Benkmann,G.Kriese,P.Bogdanski. 蒙古族、朝鲜族和壮族中腺苷酸激酶、腺苷脱氨酶、血清触珠蛋白、α1-抗胰蛋白酶的多态性[J]. 人类学学报, 1987, 6(02): 96-102.

Xu Jiujin, Cui Meiying, Li Shizhe, Chen Liangzhong, Du Ruofu, H. W. Goedde, H. G. Benkman, G. Kriese, P. Bogdanski. The polymorphism of adenylate kinase, adenosine deaminase, haptoglobin and a1-antitrypsin in Mongolian, Korean and Zhuang populations of China[J]. Acta Anthropologica Sinica, 1987, 6(02): 96-102.