十个民族转铁蛋白遗传多态性的研究

人类学学报 ›› 1991, Vol. 10 ›› Issue (03): 216-221.

十个民族转铁蛋白遗传多态性的研究

王晓明，张贵寅，于世辉，徐玖瑾

出版日期:1991-09-15 发布日期:1991-09-15

The polymorphism of transferrin in ten Chinese nationalities

Wang Xiaoming, Zhang Guiyin, Yu Shihui, Xu Jiujin

Online:1991-09-15 Published:1991-09-15

摘要/Abstract

摘要： 应用超薄层聚丙烯(月先)胺凝胶等电聚焦方法，检测了我国十个民族共2562人的转铁蛋白遗传多态性。Tf*C1基因频率依次为鄂温克族0.7571，鄂伦春族0.7467，维吾尔族0.7445，蒙古族0.7433，达斡尔族0.7417，西安汉族0.7205，满族0.7195，朝鲜族0.7136，藏族0.7096，回族0.7077，哈尔滨汉族0.7056。Tf*C2基因频率顺序基本上与Tf*C1相反。在蒙古族、西安汉族及满族中检出罕见变异型。

关键词: 转铁蛋白；遗传多态性；等电聚焦；人类遗传学

Abstract: The transferrin(Tf) polymorphism of Ew enki, Mongolian, Oroqen, Tahur, Tibetan, Man-chu, Korean, Hui, Han(Xian, Harbin), Uighur nationalities living in China was investigate?by means of ultra-thin polyacrylamide gel iso eletric focusing. The results showed that ·he·Tf*C1 gene frequencies of eleven groups were higher than 0.7: Ewenki 0.7571, Oroqen 0.7467,Uighur 0.7445, Mongolian 0.7433, Tahur 0.7417, Han(Xian) 0.7205, Manchu 0.7195, Korean0.7136, Tibetan 0.7096, Hui 0.7077, Han(Harbin) 0.7056, respectively. The Tf*C2 was the se-cond major allele in these ethnical groups. The order of . Tf*C2 allelefrequenciesroughlywas opposite to Tf*Cl. In addition, some rare phenotypes werefound, such as TfBDchi in Mongolian; TfDchiDchi in Han(Xian) and TfBCl in Manchu.

Key words: Tf; Polymorphism; IEF; Population genetics

王晓明，张贵寅，于世辉，徐玖瑾. 十个民族转铁蛋白遗传多态性的研究[J]. 人类学学报, 1991, 10(03): 216-221.

Wang Xiaoming, Zhang Guiyin, Yu Shihui, Xu Jiujin. The polymorphism of transferrin in ten Chinese nationalities[J]. Acta Anthropologica Sinica, 1991, 10(03): 216-221.