克里雅河下游封闭人群DYS19和DYS390多态性研究

人类学学报 ›› 2004, Vol. 23 ›› Issue (04): 326-330.

克里雅河下游封闭人群DYS19和DYS390多态性研究

段然慧,刘伟强,周慧,朱泓

出版日期:2004-12-15 发布日期:2004-12-15

Genetic polymorphisms of dys19 and dys390 in an “insulated” population in the lower reaches of Keriyan river

DUAN Ran-hui; LIU Wei-qiang; ZHOU Hui; ZHU Hong

Online:2004-12-15 Published:2004-12-15

摘要/Abstract

摘要： 本文以居住于塔克拉玛干沙漠当中克里雅河下游地区封闭人群（51例男性）为研究对象，采用基因扫描对其DYS19和DYS390两个STR基因座进行基因扫描研究其遗传多态性。对于DYS19基因座，克里雅河下游的封闭人群等位基因分布呈现"M"形分布，以DYS19*14和DYS19*16最常见，基因频率分别为0.353和0.510；对于DYS390基因座，其人群等位基因分布也并非呈现"钟形"分布，而是以DYS390*21和DYS390*24两种基因型基因频率最高，并且DYS390*21为此人群等位基因重复次数最少的基因型，基因频率分别为0.235和0.431，这可能是提示克里雅河下游的封闭人群的来源包含两个不同的群体分支。

关键词: Y染色体;封闭人群;STR基因座;多态性

Abstract: Two Y-linked short-tandem-repeat polymorphisms (DYS19 and DYS390) were analyzed by Genescan in an “insulated” population in the center of the Taklamakan desert of Xinjiang province. And 51 unrelated male individuals were also studied. The allelic distribution of DYS19 in this Keriyan population shows “M” shape. DYS19 ＊14 and DYS19 ＊16 are the most common allele, frequencies of which are 0.353 and 0.510, respectively. As DYS390 ＊21 owns the least repeat number and DYS390 ＊24 are the most common allele.This study suggeststhat the ancestor of Keriyan population is derived from two distinct origins.

Key words: Y-Chromosome; “Insulated” population; Short-tandem-repeat; Polymorphism

段然慧,刘伟强,周慧,朱泓. 克里雅河下游封闭人群DYS19和DYS390多态性研究[J]. 人类学学报, 2004, 23(04): 326-330.

DUAN Ran-hui; LIU Wei-qiang; ZHOU Hui; ZHU Hong. Genetic polymorphisms of dys19 and dys390 in an “insulated” population in the lower reaches of Keriyan river[J]. Acta Anthropologica Sinica, 2004, 23(04): 326-330.