关键词: 载脂蛋白B;D17S30位点;等位基因;聚合酶链反应

Abstract: The apoB and D17S30 locus, which has a high degree of polymorphism, is an important identifier that measures the value of genetic marker systems in the study of anthropology. Using polymerase chain reaction (PCR) technique, the variable number of tandem repeats (VNTR) of the apoB and D17S30 locus were studied in Korean2Chinese and people of the Han nationality of Yanbian. There was a significant difference (P < 0105) in the total distribution of allele frequencies of the apoB and D17S30 locus between these two groups. Heterozygosity, polymorphism information content and individual identification of the apoB and D17S30 were all greater than 017. These results indicate that: 1) the distribution of allele frequencies of apoB and D17S30 locus has the better degree of polymorphism in Korean-Chinese and Han nationality of Yanbian; 2) these loci are suitable for individual identification and paternity diagnosis; 3) this type of research is valuable for studying the origin of nationality, transition, national distinction and genetic relationships between nationalities.

Key words: ApoB; D17S30 locus; Allele; Polymerase chain reaction