中国内蒙古鄂伦春、鄂温克、达斡尔族人五种酶型和二种血清型遗传多样性分析

人类学学报 ›› 2005, Vol. 24 ›› Issue (01): 70-76.

中国内蒙古鄂伦春、鄂温克、达斡尔族人五种酶型和二种血清型遗传多样性分析

刘牧,沈淑萍,马栓柱,陈彩,丁鑫,赵英芳,杨宏东,童欢,郭中辉,王万胜,刘建军,堂吉斯,苏和,布仁,宝军,白立华,石刚

出版日期:2005-03-15 发布日期:2005-03-15

A study of the genetics polymorphisms of five red cell isoenzymes and two serum groups in the Oroqen, Ewenki and Dawuor Nationalities in the Chinese of Inner Mongolia

LIU Mu, SHEN Shuping, MA Shuanzhu, et al.

Online:2005-03-15 Published:2005-03-15

摘要/Abstract

摘要： 应用G6PD ACP ADA AK1和GC-Tf同步电泳的方法及GPT凝胶电泳的方法,分别对内蒙古境内鄂温克、鄂伦春、达斡尔族人476份血痕红细胞酶型:GPT、6-PGD、ACP、ADA、AK1和血清型GC、Tf的遗传多样性进行检测。根据所测表型频率分布、计算出基因频率分布,识别能力和累积识别能力,就其多态性特征及其在法医学鉴定中的应用价值进行了分析讨论。同国内外不同资料进行了比较研究,阐明了三群体上述酶型和血清型遗传多样性分布的规律和特点。从血型遗传学角度探讨了鄂伦春、鄂温克、达斡尔族间的族源、血缘关系。被调查人群中未发现各酶型和血清型的变异型。

关键词: 酶型;血清型;遗传多态性;少数民族(群体)

Abstract: Red cell isoenzymes GPT, 6-PGD, ACP, ADA, AK1 and the serum group GC-Tf are genetic polymorphisms that are inherited according to the Mendelian law of segregation. In this paper, the phenotype frequencies of the GPT, 6-PGD, ACP, ADA, AK1 and GC-Tf have been investigated by the method of typing GPT-ACP-6PGD-ADA-AK1 and Gc-Tf on the same mixed starch agarose gel electrophoresis among seven Chinese nationalities, Ewenki, Oroqen and Dawuor.
The distribution of their type frequencies varied with ethnic group and the gene frequencies, DP and CDP were also calculated. The ranges of gene frequencies of Ewenki, Oroqen and Dawuor were: GPT^1 0.46875 - 0.47225, 6-PGD^A 0.8563 - 0.8583, ACP^A 0.2139 - 0.2208, ADA^1 0.9500 - 0.9596, AK^1_1 0.9963- 1.000, Gc^1 0.64375- 0.65445, Tf^c 0.9669- 0.96945. The DP were: GPT 0.6288- 0.6303, 6-PGD 0.3999- 0.4037, Acp 0.4916- 0.5187, ADA 0.1487- 0.1800, AK_1 0- 0.0111, GC 0.5839- 0.6029, Tf 0.1147- 0.1236. No rare genes of other isoenzymes or serum groups were found.
The differences in the distribution of 5 isoenzymes and 2 serum groups in the 3 ethnic groups were analyzed. It was found that there were many similarities in the genetic characters of the Oroqen, Ewenki and Dawuor herdsmen populations addressed in the past suoluner, showing the possible common blood ties of these 3 populations, which has been recorded in the historical data.

Key words: Isoenzymes and serum group; Gene polymorphism; Ethnic group

刘牧,沈淑萍,马栓柱,陈彩,丁鑫,赵英芳,杨宏东,童欢,郭中辉,王万胜,刘建军,堂吉斯,苏和,布仁,宝军,白立华,石刚. 中国内蒙古鄂伦春、鄂温克、达斡尔族人五种酶型和二种血清型遗传多样性分析[J]. 人类学学报, 2005, 24(01): 70-76.

LIU Mu, SHEN Shuping, MA Shuanzhu, et al.. A study of the genetics polymorphisms of five red cell isoenzymes and two serum groups in the Oroqen, Ewenki and Dawuor Nationalities in the Chinese of Inner Mongolia[J]. Acta Anthropologica Sinica, 2005, 24(01): 70-76.