人类学学报 ›› 2022, Vol. 41 ›› Issue (04): 764-774.doi: 10.16359/j.1000-3193/AAS.2022.0025
• • 上一篇
收稿日期:
2022-03-24
修回日期:
2022-05-09
出版日期:
2022-08-12
发布日期:
2022-08-10
作者简介:
崔银秋,教授,研究方向是古微生物学与人类遗传。Email: 基金资助:
CUI Yinqiu1,2(), ZHANG Hao2, WU Xiyan3, SUN Bing2, ZHOU Hui2
Received:
2022-03-24
Revised:
2022-05-09
Online:
2022-08-12
Published:
2022-08-10
摘要:
古代病原微生物基因组研究对病理学、微生物学、考古学等领域均具有重要的价值。在过去的十年里,高通量测序和靶向富集技术的发展和应用使古代微生物基因组的获取成为可能,通过对古代人群样本中获取的宏基因组进行筛查,使得引发古代疫情的相关病原体的基因组得以重建,为研究人类传染病的起源、传播和演化提供了一个独特的窗口。在当今全球化的背景下,新发及再发传染性疾病的出现频率促使我们回顾过去,以便更好地了解现代病原菌出现和古代病原菌重新出现的过程和生态环境。在这篇文章中,我们总结了近十年古代病原微生物基因组水平的研究进展,并提出了这项研究所面临的挑战以及未来的研究前景和方向。
中图分类号:
崔银秋, 张昊, 武喜艳, 孙冰, 周慧. 古代病原微生物基因组的研究进展[J]. 人类学学报, 2022, 41(04): 764-774.
CUI Yinqiu, ZHANG Hao, WU Xiyan, SUN Bing, ZHOU Hui. Progress in genomes of ancient pathogenic microorganisms[J]. Acta Anthropologica Sinica, 2022, 41(04): 764-774.
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