人类学学报 ›› 1991, Vol. 10 ›› Issue (04): 321-323.

• 人类学学报 • 上一篇    下一篇

我国汉族人群的乙二醛酶Ⅰ遗传多态性

李实喆,杜若甫   

  • 出版日期:1991-12-15 发布日期:1991-12-15

Polymorphism of human red cell glyoxalase 1 in Han populations of China

Li shizhe, Du Ruofu   

  • Online:1991-12-15 Published:1991-12-15

摘要: 用琼脂糖平板凝胶电泳技术分析了我国六个城市的汉族共1238人的红细胞乙二醛酶I的遗传多态性。每个汉族人群的受检人数和GLO1*1基因频率分别为:郑州200人(0.1023),哈尔滨195人(0.1103),呼和浩特210人(0.1259),贵阳204人(0.1373),兰州210人(0.1476),西安199人(0.1508)。中国不同地区汉族人群之间的GLOI基因频率分布存在显著性差异,但这种差异明显小于中国不同少数民族之间的差异。

关键词: 汉族;乙二醛酶;遗传多态性

Abstract: The polymorphism of human red cell glyoxalase I was studied inHan subpopulationsfrom six cities by agarose gel electrophoresis. The frequency of GLOI*1 gene and the numberof testes in each subpopulation are as follows: Zhengzhou 0. 1023(220), Harbin 0. 1103(195),Huhhot 0. 1259(210), Guiyang 0. 1373(204), Lanzhou 0.1476(210) and Xi'an 0.1508(199). Asignificant difference of frequencies of GLO I gene was found between the Zhengzhou andLanzhou Han subpopulations. The difference of gene frequencies between Han subpopulationsis evidently smaller than that between ethnic groups in China.

Key words: Han; Glyoxalase; Genetic polymorphism