关键词: 结合珠蛋白；遗传多态性

Abstract: By means of vertical slab polyacrylamide gel electrophoresis this article deals with the Hpphenotypes of 918 individuals in the Guilin population. The common phenotype frequencies ofHp occurring in the Guilin population are as follows: Hpl-1 0.121; Hp2-2 0.425; Hp2-1 0.439and Hp0 0.0153. The gene frequencies of Hp^1 and Hp^2were0.340 and 0.644, respectively.Besides these four common Hp types some variants have also been discovered,namely, 2-1(Haw), 2-1J, 2-H, C-1 and 2-Z. Among them, the variants of C-1 and 2-Z were not available in the literature. The frequencies of various phenotypes of Hp occurring in males and fe-males are as follows: Hp1-1, (male) 0.101, (female)0.135; Hp2-1, (male)0.475, (female)0.409; Hp2-2, (male)0.405, (female)0.446and Hp0, (male)0.020, (female)0.010. It was also noted that the gene frequencies of Hp^1 occurring in different age groups (15--24, 25--34, 35--66)are basically the same.

Key words: Haptoglobin; Genetic poly norphism