组特异性成份(Gc)亚型在六个民族中的分布

人类学学报 ›› 1993, Vol. 12 ›› Issue (02): 175-181.

组特异性成份(Gc)亚型在六个民族中的分布

尹娇杨，张贵寅，于世辉，王晓明

出版日期:1993-06-15 发布日期:1993-06-15

The distribution of the subtypes of Group-Specific Component (Gc) of six nationalities in north China

Yin Jiaoyang, Zhang Guiyin, Yu Shihui, Wang Xiaoming

Online:1993-06-15 Published:1993-06-15

摘要/Abstract

摘要： 应用超薄层聚丙烯酰胺凝胶等电聚焦电泳技术结合改良的磺基水杨酸沉淀法(PharmalytepH4.5-5.4)检测了中国六个民族1 021名彼此无关的血清的Gc亚型。哈尔滨汉族、鄂温克族、达翰尔族、蒙古族、鄂伦春族、锡伯族的Gc 1F基因频率分别为0.4246、0.4941、0.4479、0.4107、0.4606、0.4503；Gc 1S的基因频率分别为0.2587、0.2936、0.3151、0.2798、0.3370、0.3035；Gc 2的基因频率分别为0.3065、0.2064、0.2266、0.3006、0.2022、0.2388。在五个民族中发现了十六名个体携带罕见的Gc等位基因(1A2、1A6、1A7、1A9、1C2、1C3、1C4、1C10、2A? )。

关键词: 组特异性成份；遗传多态性；人类群体遗传学

Abstract: The frequencies of Gc subtypes of six nationalties in north China were studied by isoelectric focusing on ultra- thin polyacrylamide gel followed by the improved sulfosalicylic acid precipitation. The gene frequencies of Gc1F in Han (Harbin) , Ewenki, Tahur, M ongolian, Oroqen and Xibo nationalities were0.4246, 0.4941, 0.4479, 0.4107, 0.4606, 0.4503; those of Gc1Swere 0.2587, 0.2936, 0.3151, 0.2798, 0.3370, 0.3035 and those of Gc2 were 0. 3065, 0.2064,0.2266, 0.3006, 0.2022, 0.2388, respectively. In addition, 16 persons who had rare variant alleles of Gc (1A2, 1A6, 1A7 lA9, 1C2, 1C3, 1C4, 1C10, 2A) were found in five nationalitties.

Key words: Group-Specific Component (Gc); Genetic polymorphism; Human population genetics

尹娇杨，张贵寅，于世辉，王晓明. 组特异性成份(Gc)亚型在六个民族中的分布[J]. 人类学学报, 1993, 12(02): 175-181.

Yin Jiaoyang, Zhang Guiyin, Yu Shihui, Wang Xiaoming. The distribution of the subtypes of Group-Specific Component (Gc) of six nationalities in north China[J]. Acta Anthropologica Sinica, 1993, 12(02): 175-181.