Abstract: The distribution of Lewis, ABO, MN, Rh, P blood groups and ABH secretion in Han nationality of North China was examined. In common with other populations of Han nationality in North China, the present population revealed a high frequency of IB (0.2135), and a slightly higher frequency of n (0.5016) than that of m (0.4984). High frequency of Le (a + ) (24.17%) was observed. Among 94 individuals tested, 4 cases of Le (a + ) were found to be ABH secretor secreting A or B substances but not H substance. A total o￡ 638 specimens was tested for Rh (D) and only 2 (0.31%) of Rh(D) negative were found. Pi gene frequency appeared to be 0.2131. A lower Se gene frequency (0.4761) for ABH secretion in comparison with other nationalities of China was obtained.

Key words: Human population genetics; Gene frequency of blood groups; Lewis blood group; ABO blood group; MN blood group; Rh blood group; P blood group； ABH secretion