Abstract: The distribution of Gc subtypes of four ethnic groups in China was studied with isoelectric focusing followed by immunofixation. The Gc1F gene frequencies of Bai, Miao, Tujia and Yi were 0. 4082, 0. 4229, 0. 3592, 0. 4248; Gc1s were 0. 3035, 0. 2687, 0. 2864, 0. 3301; and Gc2 were 0. 2577, 0. 3035, 0. 3342, 0. 2208, respectiveiy. In addition, 16 persons who had rare variant alleles of Gc were found in these ethnic groups.

Key words: Group specific components (Gc); Genetic polymorphisms; Human population genetics; National minorities in China