Abstract: By using the gene frequencies of esterase D, acid phosphorase, glutamate-puruvate- transaminase and 6-phosphogluconate-dehydrogenase, the genetictopological analysis was carried out on 16 national minoritier and 5 subpopulationsof the Han ethnic group in China. The dimensional eigenvectorial representations calculated on the basis of genetic distances between 21 populations were fitted to maximum congruence: with those calculated on the basis of geographical distances,and the origin,kinship and migration of these populations were discussed.

Key words: Genetic topology; Chinese; Population genetics