Genetic Polymorphism of 13 RM Y-STR Loci in Shandong Population

  • Yuling CHEN ,
  • Min LI ,
  • Zhenmin ZHAO ,
  • Yanan Li ,
  • Yun BAO ,
  • Ruxin ZHU ,
  • Xiang SHENG ,
  • Yali WANG ,
  • Xingyuan MA
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  • 1. School of Biotechnology and State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237
    2. Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Institute of Forensic Science, Ministry of Justice, Shanghai 200063

Received date: 2017-02-15

  Revised date: 2017-05-21

  Online published: 2020-09-10

Abstract

To verify the allele frequency and the haplotype diversity of the 13 rapidly mutating (RM) Y-STRs in Shandong province, Chinese Han population, we collected 154 unrelated male blood samples on FTA cards, and amplified the 13 RM Y-STRs with multiple PCR and tested the genotype using 3130XL (ABI) Genetic Analyzer. Among 13 RM Y-STRs, we observed a total of 331 alleles, and the values of gene diversity for each STR ranged from 0.7643 (DYS576) ~ 0.9946 (DYF399S1abc). Altogether 154 different haplotypes were identified from 154 unrelated male individuals and the haplotype diversity reached 1. We make a Conclusion that 13 RM Y-STRs show strong discrimination power and great application value for forensic in Shandong Han population.

Cite this article

Yuling CHEN , Min LI , Zhenmin ZHAO , Yanan Li , Yun BAO , Ruxin ZHU , Xiang SHENG , Yali WANG , Xingyuan MA . Genetic Polymorphism of 13 RM Y-STR Loci in Shandong Population[J]. Acta Anthropologica Sinica, 2019 , 38(02) : 292 -303 . DOI: 10.16359/j.cnki.cn11-1963/q.2017.0073

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